Spatial Distribution and Predictive Significance of Dendritic Cells and Macrophages in Esophageal Cancer Treated With Combined Chemoradiotherapy and PD-1 Blockade

BackgroundThe first clinical study (NCT03671265) of first-line chemoradiotherapy combined with PD-1 blockade showed promising treatment outcomes in locally advanced esophageal squamous cell carcinoma (ESCC).However, partial patients did not respond to the combination treatment.The roles of dendritic cells (DCs) and macrophages in this combination t

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THE DYNAMICS OF THE COLLECTION OF THE MANDATORY STATE PENSION FUND CONTRIBUTION (WITH THE EXAMPLE OF THE FORMATION OF JUDICIAL PRACTICE)

The subject of the study is the conceptual, theoretical, methodological and applied Cosmetic Bag provisions of mandatory state pension insurance in Ukraine through the lens of its regulatory framework and judicial application.Methodology.General scientific methods were used in the research process.The method of comparison was used to generalise the

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Thymol polymeric nanoparticle synthesis and its effects on the toxicity of high glucose on OEC cells: involvement of growth factors and integrin-linked kinase

Elahe Karimi,1,2 Shahryar Abbasi,1,3 Naser Abbasi2,41Department of Chemistry, Ilam Branch, Islamic Azad University, Ilam, Iran; 2Biotechnology and Medicinal Cabochons Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran; 3Department of Chemistry, Faculty of Science, Ilam University, Ilam, Iran; 4Department of Pharmacolo

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